STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0607ABC transporter, permease component, putative; GC: 46.94%; Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.754. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.999); Curator(s): D. Akan, J. Alves. (778 aa)    
Predicted Functional Partners:
mefE
Macrolide-efflux protein, putative; GC: 45.79%; Transporter classification TC:2.A.1.21.1. Transmembrane domains: 12. Codon Adaptation Index (CAI): 0.759. Curator(s): D. Akan, J. Alves.
 
     0.926
SSA_0606
ABC-type antimicrobial peptide transport system, ATPase component, putative; GC: 49.33%; Transporter classification TC:3.A.1.122.1. Codon Adaptation Index (CAI): 0.735. Curator(s): D. Akan, J. Alves; Protein involved in nucleoside-triphosphatase activity.
 
   0.841
SSA_0609
Transcriptional regulator, TetR/AcrR family, putative; GC: 43.2%; Codon Adaptation Index (CAI): 0.759. Curator(s): D. Akan, J. Alves; Protein involved in regulation of transcription.
 
     0.840
SSA_2012
Conserved hypothetical protein; GC: 39.79%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.781. Curator(s): T. Kitten, J. Alves.
  
     0.505
SSA_1645
Conserved hypothetical protein; GC: 42.9%; Codon Adaptation Index (CAI): 0.762.
 
     0.472
SSA_0441
Conserved hypothetical protein; GC: 40.16%; Codon Adaptation Index (CAI): 0.793. Helix-turn-helix prediction: AraC. Curator(s): M. Chaplin; Protein involved in regulation of transcription.
 
     0.457
gidB
Methyltransferase gidB, putative; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
    0.442
htpX
HtpX protease, putative; GC: 48.05%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.784. SignalP prediction: Yes (prob. 0.893); Curator(s): D. Akan; Protein involved in hydrolase activity and metal ion binding; Belongs to the peptidase M48B family.
       0.411
SSA_0961
Possible ketopantoate reductase PanE/ApbA, putative; GC: 39.3%; Codon Adaptation Index (CAI): 0.777. Curator(s): T. Kitten; Protein involved in 2-dehydropantoate 2-reductase activity.
  
     0.411
lemA
LemA-like protein, putative; GC: 43.33%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.819. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.791); Curator(s): D. Akan.
       0.410
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.