STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gtfPGlucosyltransferase, putative; GC: 44.13%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.796. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.998); Curator(s): P. Xu; Protein involved in transferase activity and dextransucrase activity. (1568 aa)    
Predicted Functional Partners:
gtfA
Dextransucrase, putative; GC: 41.84%; Codon Adaptation Index (CAI): 0.798; Protein involved in transferase activity, transferring glycosyl groups, dextransucrase activity and carbohydrate metabolism.
     
 0.918
scrB
Sucrose-6-phosphate hydrolase, putative; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
   
 
 0.902
pcsB
Secreted antigen GbpB/SagA; GC: 42.63%; Codon Adaptation Index (CAI): 0.794. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves.
      
 0.651
SSA_0004
Lipoprotein, putative; GC: 33.13%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.811. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves.
  
     0.636
gtrB
Glycosyltransferase (vectorial glycosyl polymerization (VGP) family), putative; GC: 45.52%; Transporter classification TC:9.B.32.1.3. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.773. Curator(s): L. Ozaki; Protein involved in transferase activity.
      
 0.623
gtfB
GtfB, putative; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
  
   
 0.613
SSA_0258
Conserved hypothetical protein; GC: 47.27%; Codon Adaptation Index (CAI): 0.787. Curator(s): P. Manque.
  
     0.597
rgg
Rgg protein, putative; GC: 39.8%; Codon Adaptation Index (CAI): 0.785. Curator(s): P. Xu; Protein involved in DNA binding and regulation of transcription, DNA-dependent.
     
 0.572
SSA_0179
Conserved hypothetical protein; GC: 40.18%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.761. Curator(s): M. Serrano, J. Alves; possibly membrane-associated.
  
     0.558
srtA
Sortase, putative; GC: 40.08%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.796. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.658); Protein involved in transferase activity.
      
 0.472
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.