Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
SSA_0621SOS responce UmuC protein, putative; GC: 48.31%; Codon Adaptation Index (CAI): 0.751. Curator(s): P. Xu; Protein involved in DNA repair. (471 aa)    
Predicted Functional Partners:
SSA_0620
Conserved hypothetical protein; GC: 48.27%; Codon Adaptation Index (CAI): 0.75. Curator(s): P. Xu.
 
     0.934
dnaN
DNA polymerase III, beta chain, putative; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...]
   
 0.861
SSA_0622
XRE family transcriptional regulator; GC: 46.02%; Codon Adaptation Index (CAI): 0.741. Curator(s): P. Xu, J. Alves; Protein involved in serine-type peptidase activity.
 
    0.828
SSA_0618
Conserved hypothetical protein; GC: 40.48%; Codon Adaptation Index (CAI): 0.756. Curator(s): P. Xu.
       0.805
recA
RecA protein, putative; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.704
polA
DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.608
dnaE
DNA-polymerase III alpha-chain, putative; GC: 46.17%; Codon Adaptation Index (CAI): 0.784. Curator(s): L. Ozaki; Protein involved in 3'-5' exonuclease activity and nucleotidyltransferase activity.
  
  
 0.528
SSA_0623
Membrane protein, putative; GC: 39.06%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.764. Curator(s): P. Xu.
       0.527
dinG
ATP-dependent DNA helicase; 3'-5' exonuclease.
  
 
 0.467
snf
Snf2 family protein, putative; GC: 45.39%; Codon Adaptation Index (CAI): 0.785; Protein involved in ATP binding.
   
 0.448
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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