Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0629Conserved hypothetical protein; GC: 43.52%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.784. Helix-turn-helix prediction: AraC. Curator(s): P. Xu. (179 aa)    
Predicted Functional Partners:
SSA_0627
Conserved hypothetical protein; GC: 43.3%; Codon Adaptation Index (CAI): 0.821. Curator(s): P. Xu.
       0.855
rlmN
Fe-S-cluster redox enzyme/radical SAM enzyme, Cfr family, putative; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
       0.855
SSA_0624
Conserved hypothetical protein; GC: 48.7%; Codon Adaptation Index (CAI): 0.759. Curator(s): P. Xu; Protein involved in transferase activity.
       0.684
kdtB
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.684
SSA_0626
Conserved hypothetical protein; GC: 46.07%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.772. SignalP prediction: Yes (prob. 0.451); Curator(s): P. Xu; Protein involved in protein binding.
       0.684
SSA_1402
ABC-type multidrug transport system, ATPase and permease components, putative; GC: 45.8%; Transporter classification TC:3.A.1.106.1. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.778. SignalP prediction: Yes (prob. 0.98); Curator(s): J. Alves; Protein involved in ATPase activity, coupled to transmembrane movement of substances.
       0.450
SSA_1403
Multidrug ABC transporter, ATPase and permease components, putative; GC: 47.1%; Transporter classification TC:3.A.1.106.1. Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.775. SignalP prediction: Yes (prob. 0.997); Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in ATPase activity, coupled to transmembrane movement of substances.
       0.450
SSA_1636
ABC-type antibiotic exporter, ATPase component, putative; GC: 50.06%; Transporter classification TC:3.A.1.120.3. Codon Adaptation Index (CAI): 0.771. Curator(s): J. Alves; Protein involved in nucleoside-triphosphatase activity.
       0.450
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: medium (44%) [HD]