STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpCIndole-3-glycerol phosphate synthase, putative; GC: 44.01%; Codon Adaptation Index (CAI): 0.77. Curator(s): P. Xu; Protein involved in tryptophan metabolism; Belongs to the TrpC family. (255 aa)    
Predicted Functional Partners:
trpG
Anthranilate synthase component II, putative; GC: 45.21%; Codon Adaptation Index (CAI): 0.783. Curator(s): P. Xu; Protein involved in folic acid biosynthesis.
  
 0.999
trpD
Anthranilate phosphoribosyltransferase, putative; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.999
trpF
N-(5'-phosphoribosyl)anthranilate isomerase, putative; GC: 48.9%; Codon Adaptation Index (CAI): 0.762. Curator(s): P. Xu; Protein involved in isomerase activity; Belongs to the TrpF family.
 
 0.999
trpB
Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpA
Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.999
trpE
Anthranilate synthase component I, putative; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and hig [...]
 
 0.998
trpB2
Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.996
pabB
Anthranilate/para-aminobenzoate synthases component I/ Chorismate binding enzyme, putative; GC: 49.3%; Codon Adaptation Index (CAI): 0.761. Curator(s): M. Chaplin, J. Alves.
 
 
 0.964
pheA
Prephenate dehydratase, putative; GC: 47.48%; Codon Adaptation Index (CAI): 0.75; Protein involved in amino acid binding.
 
  
 0.677
SSA_1183
Conserved hypothetical protein; GC: 42.8%; Codon Adaptation Index (CAI): 0.794.
  
  
 0.645
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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