| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| glyA | ilvA | SSA_1155 | SSA_1967 | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.928 |
| glyA | serB | SSA_1155 | SSA_0882 | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | 0.922 |
| glyA | trpA | SSA_1155 | SSA_0638 | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.977 |
| glyA | trpB | SSA_1155 | SSA_0637 | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.909 |
| glyA | trpB2 | SSA_1155 | SSA_0631 | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.909 |
| ilvA | glyA | SSA_1967 | SSA_1155 | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
| ilvA | serB | SSA_1967 | SSA_0882 | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | 0.904 |
| ilvA | trpA | SSA_1967 | SSA_0638 | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.914 |
| ilvA | trpB | SSA_1967 | SSA_0637 | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.924 |
| ilvA | trpB2 | SSA_1967 | SSA_0631 | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.924 |
| serB | glyA | SSA_0882 | SSA_1155 | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.922 |
| serB | ilvA | SSA_0882 | SSA_1967 | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.904 |
| serB | trpA | SSA_0882 | SSA_0638 | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
| serB | trpB | SSA_0882 | SSA_0637 | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.913 |
| serB | trpB2 | SSA_0882 | SSA_0631 | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.913 |
| trpA | glyA | SSA_0638 | SSA_1155 | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.977 |
| trpA | ilvA | SSA_0638 | SSA_1967 | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Threonine desaminase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.914 |
| trpA | serB | SSA_0638 | SSA_0882 | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity. | 0.900 |
| trpA | trpB | SSA_0638 | SSA_0637 | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
| trpA | trpB2 | SSA_0638 | SSA_0631 | Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Tryptophan synthase beta chain, putative; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
