node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSA_0657 | divIVA | SSA_0657 | SSA_0660 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | 0.760 |
SSA_0657 | ftsA | SSA_0657 | SSA_0655 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.837 |
SSA_0657 | ftsZ | SSA_0657 | SSA_0656 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Cell division protein FtsZ, putative; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.815 |
SSA_0657 | murD | SSA_0657 | SSA_0652 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.565 |
SSA_0657 | murF | SSA_0657 | SSA_0692 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | D-Ala-D-Ala adding enzyme, putative; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.576 |
SSA_0657 | murG | SSA_0657 | SSA_0653 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.568 |
SSA_0657 | pdxK | SSA_0657 | SSA_1400 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyridoxal kinase, putative; GC: 44.64%; Codon Adaptation Index (CAI): 0.746; Protein involved in transferase activity and kinase activity. | 0.647 |
SSA_0657 | pfs | SSA_0657 | SSA_1639 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.623 |
SSA_0657 | rlmN | SSA_0657 | SSA_0628 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Fe-S-cluster redox enzyme/radical SAM enzyme, Cfr family, putative; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.562 |
SSA_0657 | sepF | SSA_0657 | SSA_0658 | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Conserved uncharacterized protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.958 |
divIVA | SSA_0657 | SSA_0660 | SSA_0657 | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.760 |
divIVA | ftsA | SSA_0660 | SSA_0655 | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.746 |
divIVA | ftsZ | SSA_0660 | SSA_0656 | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | Cell division protein FtsZ, putative; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.702 |
divIVA | murD | SSA_0660 | SSA_0652 | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.467 |
divIVA | murG | SSA_0660 | SSA_0653 | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.486 |
divIVA | sepF | SSA_0660 | SSA_0658 | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | Conserved uncharacterized protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.814 |
ftsA | SSA_0657 | SSA_0655 | SSA_0657 | Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.837 |
ftsA | divIVA | SSA_0655 | SSA_0660 | Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. | 0.746 |
ftsA | ftsZ | SSA_0655 | SSA_0656 | Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division protein FtsZ, putative; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.997 |
ftsA | murD | SSA_0655 | SSA_0652 | Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.871 |