Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
divIVACell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division. (264 aa)    
Predicted Functional Partners:
sepF
Conserved uncharacterized protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.952
ftsA
Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
  
 0.928
ftsZ
Cell division protein FtsZ, putative; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.912
SSA_0657
PyridoxaL 5'-phosphate Dependent Enzymes class III, putative; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.892
SSA_0659
Conserved hypothetical protein; GC: 40.08%; Codon Adaptation Index (CAI): 0.793. Curator(s): P. Xu, J. Alves; contains S4-like RNA-binding domain; Protein involved in RNA binding.
 
    0.874
pkn
Serine/threonine protein kinase, putative; GC: 45.95%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.786; Protein involved in transferase activity.
  
 
 0.834
divIB
Cell division protein DivIB, putative; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
   
 0.796
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
  
 0.781
pabC
Aminodeoxychorismate lyase, putative; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
   
 0.758
mreC
Cell shape determining protein MreC, putative; Involved in formation and maintenance of cell shape.
   
 
 0.737
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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