Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0665NTP pyrophosphohydrolases including oxidative damage repair enzymes (MutT/NUDIX family); GC: 46.67%; Codon Adaptation Index (CAI): 0.792. Curator(s): P. Xu, J. Alves; Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. (149 aa)    
Predicted Functional Partners:
SSA_0664
Conserved uncharacterized protein; GC: 35.97%; Codon Adaptation Index (CAI): 0.798. Curator(s): P. Xu, J. Alves.
 
     0.866
birA
Biotin--[acetyl-CoA-carboxylase] ligase, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.595
SSA_1844
Conserved hypothetical protein; GC: 40.52%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.787.
  
     0.592
SSA_0670
Conserved uncharacterized protein; GC: 39.83%; Codon Adaptation Index (CAI): 0.788. Curator(s): P. Xu.
 
     0.565
SSA_0666
Hypothetical protein; GC: 32.41%; Codon Adaptation Index (CAI): 0.818. Curator(s): P. Xu.
       0.561
SSA_0354
Uncharacterized membrane protein; GC: 44.02%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.782. Required for colicin V production. Curator(s): T. Kitten.
 
     0.532
vacB
Exoribonuclease, VacB/Rnb family, putative; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
 0.507
cinA
Competence-damage protein, putative; GC: 47.33%; Codon Adaptation Index (CAI): 0.77. Helix-turn-helix prediction: AraC; Protein involved in Mo-molybdopterin cofactor biosynthesis and establishment of competence for transformation; Belongs to the CinA family.
 
   
 0.477
hisK
Conserved hypothetical protein; GC: 47.87%; Codon Adaptation Index (CAI): 0.728; Belongs to the PHP hydrolase family. HisK subfamily.
 
    0.475
SSA_1608
Conserved hypothetical protein; GC: 42.68%; Codon Adaptation Index (CAI): 0.812; Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family.
 
    0.465
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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