STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0670Conserved uncharacterized protein; GC: 39.83%; Codon Adaptation Index (CAI): 0.788. Curator(s): P. Xu. (76 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, putative; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.681
SSA_1903
Conserved hypothetical protein; GC: 47.55%; Codon Adaptation Index (CAI): 0.759.
  
     0.636
nnrD
Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
       0.609
SSA_0665
NTP pyrophosphohydrolases including oxidative damage repair enzymes (MutT/NUDIX family); GC: 46.67%; Codon Adaptation Index (CAI): 0.792. Curator(s): P. Xu, J. Alves; Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family.
 
     0.565
SSA_0238
Conserved hypothetical protein; GC: 45.65%; Codon Adaptation Index (CAI): 0.727. Curator(s): P. Manque.
  
     0.550
SSA_0664
Conserved uncharacterized protein; GC: 35.97%; Codon Adaptation Index (CAI): 0.798. Curator(s): P. Xu, J. Alves.
 
     0.540
clpE
ATP dependent protease, putative; GC: 49.01%; Codon Adaptation Index (CAI): 0.786. Helix-turn-helix prediction: AraC. Curator(s): P. Xu; Protein involved in nucleoside-triphosphatase activity and unfolded protein binding; Belongs to the ClpA/ClpB family.
       0.535
SSA_0831
Nucleotide sugar synthetase-like protein, putative; GC: 49.65%; Codon Adaptation Index (CAI): 0.782. Curator(s): L. Ozaki.
  
     0.504
ispA
Farnesyl diphosphate synthase, putative; GC: 46.8%; Codon Adaptation Index (CAI): 0.77. Curator(s): P. Xu; Belongs to the FPP/GGPP synthase family.
  
    0.496
SSA_1789
Metal-dependent phosphohydrolase, HD superfamily, putative; GC: 45.93%; Codon Adaptation Index (CAI): 0.786. Curator(s): J. Alves; Protein involved in hydrolase activity.
  
     0.494
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.