Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xseBExodeoxyribonuclease VII small subunit, putative; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (70 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease VII large subunit, putative; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
 
 0.999
ispA
Farnesyl diphosphate synthase, putative; GC: 46.8%; Codon Adaptation Index (CAI): 0.77. Curator(s): P. Xu; Belongs to the FPP/GGPP synthase family.
  
  
 0.940
recN
DNA repair and genetic recombination, putative; May be involved in recombinational repair of damaged DNA.
 
   
 0.895
hlyA
rRNA methylase, putative; GC: 49.26%; Codon Adaptation Index (CAI): 0.779. Curator(s): P. Xu; Protein involved in hemolysis of host red blood cells.
  
    0.864
ahrC
Transcriptional regulator, ArgR family, putative; Regulates arginine biosynthesis genes.
       0.855
pphA
Serine/threonine protein phosphatase, putative; GC: 46.36%; Codon Adaptation Index (CAI): 0.784. Curator(s): P. Xu; Protein involved in hydrolase activity.
       0.737
recJ
Single-stranded DNA-specific exonuclease, 5'-3', putative; GC: 46.24%; Codon Adaptation Index (CAI): 0.791. Helix-turn-helix prediction: AraC; Protein involved in 5'-3' exonuclease activity.
  
  
 0.735
nnrD
Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
       0.693
folD
Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, putative; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.676
SSA_0683
DNA-binding protein HU, putative; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
   
 
 0.634
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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