Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
furFe2+/Zn2+ uptake regulation protein, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.786. Curator(s): P. Xu; Protein involved in regulation of transcription, DNA-dependent; Belongs to the Fur family. (147 aa)    
Predicted Functional Partners:
SSA_0101
Conserved uncharacterized protein; GC: 48.17%; Codon Adaptation Index (CAI): 0.81. Curator(s): M. Serrano.
  
    0.783
rpoA
DNA-directed RNA polymerase, alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.759
polA
DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.584
opuAb
ABC transporter, glycine-betaine/proline permease protein, putative; GC: 49.22%; Transporter classification TC:3.A.1.12.5. Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.772. Curator(s): T. Kitten.
     
 0.573
ctpA
Copper-translocating P-type ATPase, putative; GC: 47.93%; Transporter classification TC:3.A.3.5.1. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.753. LipoP prediction: SpI. Helix-turn-helix prediction: AraC. Curator(s): M. Serrano; Protein involved in metal ion transporter activity.
     
 0.561
birA
Biotin--[acetyl-CoA-carboxylase] ligase, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.556
rpoD
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32), putative; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.539
sodA
Mn/Fe-dependent superoxide dismutase, putative; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.538
nadR
ATPase/kinase, putative; GC: 45.33%; Codon Adaptation Index (CAI): 0.804. Possibly involved in NAD metabolism. Curator(s): J. Alves; Protein involved in nucleotidyltransferase activity and regulation of transcription.
  
    0.515
purL
Phosphoribosylformylglycinamidine synthase, putative; GC: 48.7%; Codon Adaptation Index (CAI): 0.782. Curator(s): J. Alves; Protein involved in catalytic activity and ligase activity.
     
 0.502
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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