STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
recRRecombinational DNA repair protein (RecF pathway), putative; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa)    
Predicted Functional Partners:
recO
DNA repair protein recO, putative; Involved in DNA repair and RecF pathway recombination.
 
 
 
 0.954
SSA_0326
Conserved uncharacterized BCR, YbaB family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.954
recF
DNA replication and repair protein recF, putative; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
 
 
 0.930
pbp2b
Penicillin-binding protein 2B, putative; GC: 48.57%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.767. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.995); Curator(s): P. Xu; Protein involved in penicillin binding and cell wall biosynthesis (sensu Bacteria).
 
  
 0.909
ddlA
D-ala,D-ala ligase, putative; Cell wall formation.
 
   
 0.909
murF
D-Ala-D-Ala adding enzyme, putative; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
     
 0.877
dnaX
DNA-directed DNA polymerase III chain, putative; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
 0.782
recJ
Single-stranded DNA-specific exonuclease, 5'-3', putative; GC: 46.24%; Codon Adaptation Index (CAI): 0.791. Helix-turn-helix prediction: AraC; Protein involved in 5'-3' exonuclease activity.
 
   
 0.728
pcrA
ATP-dependent DNA helicase, putative; GC: 48.01%; Codon Adaptation Index (CAI): 0.775. Curator(s): L. Ozaki; Protein involved in DNA repair.
 
   
 0.665
cinA
Competence-damage protein, putative; GC: 47.33%; Codon Adaptation Index (CAI): 0.77. Helix-turn-helix prediction: AraC; Protein involved in Mo-molybdopterin cofactor biosynthesis and establishment of competence for transformation; Belongs to the CinA family.
  
  
 0.652
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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