Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
citBAconitase A, putative; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (887 aa)    
Predicted Functional Partners:
SSA_0703
Citrate synthase, putative; GC: 46.92%; Codon Adaptation Index (CAI): 0.773. Curator(s): P. Xu; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; Belongs to the citrate synthase family.
 
 0.999
SSA_0704
Isocitrate dehydrogenase [NADP], putative; GC: 47.95%; Codon Adaptation Index (CAI): 0.768. Curator(s): P. Xu; Protein involved in oxidoreductase activity.
 
 0.999
ldh
L-lactate dehydrogenase, putative; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.878
phaB
Enoyl-CoA hydratase/carnithine racemase, putative; GC: 43.69%; Codon Adaptation Index (CAI): 0.819. Curator(s): J. Alves; Protein involved in lyase activity and metabolism.
   
 0.809
sodA
Mn/Fe-dependent superoxide dismutase, putative; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.787
rpmF
50S ribosomal protein L32, putative; GC: 48.09%; Codon Adaptation Index (CAI): 0.761; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.786
rplS
50S ribosomal protein L19, putative; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.759
uncA
Proton-translocating ATPase, F1 sector, alpha subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.756
rpsF
30S ribosomal protein S6, putative; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.753
leuB
3-isopropylmalate dehydrogenase, putative; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.750
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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