Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
epsHExopolysaccharide biosynthesis protein, acetyltransferase, putative; GC: 43.83%; Codon Adaptation Index (CAI): 0.762. Curator(s): P. Xu; Protein involved in transferase activity. (288 aa)    
Predicted Functional Partners:
SSA_0709
Conserved hypothetical protein; GC: 46.59%; Codon Adaptation Index (CAI): 0.76. Curator(s): P. Xu; Protein involved in DNA repair; Belongs to the UPF0213 family.
  
    0.778
SSA_0711
Conserved hypothetical protein; GC: 46.72%; Codon Adaptation Index (CAI): 0.765. Curator(s): P. Xu; Protein involved in transferase activity; Belongs to the methyltransferase superfamily.
       0.773
ctpE
P-type ATPase-metal cation transport (calcium efflux), putative; GC: 48.68%; Transporter classification TC:3.A.3.2.4. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.758. Curator(s): P. Xu, J. Alves; Protein involved in metal ion binding and hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances.
       0.495
SSA_2220
Galactosyltransferase, putative; GC: 41.42%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.8. SignalP prediction: Yes (prob. 0.989); Protein involved in transferase activity and transferase activity, transferring glycosyl groups.
  
  
 0.453
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.