Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
comECCompetence protein, putative; GC: 43.24%; Transporter classification TC:3.A.11.1.1. Transmembrane domains: 9. Codon Adaptation Index (CAI): 0.763. Helix-turn-helix prediction: AraC. Curator(s): X. Ge, J. Alves; Protein involved in establishment of competence for transformation. (746 aa)    
Predicted Functional Partners:
comEA
DNA uptake protein, putative; GC: 46.11%; Transporter classification TC:3.A.11.1.1. Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.777. SignalP prediction: Yes (prob. 0.536); Curator(s): X. Ge, J. Alves; Protein involved in establishment of competence for transformation.
 
  
 0.982
comFC
Late competence protein, putative; GC: 38.14%; Codon Adaptation Index (CAI): 0.779; Protein involved in transferase activity, transferring glycosyl groups.
 
  
 0.855
smf
DNA processing Smf protein, putative; GC: 42.11%; Codon Adaptation Index (CAI): 0.781; Protein involved in DNA mediated transformation.
 
  
 0.849
comFA
Superfamily II ATP-dependent DNA/RNA helicase; GC: 42.57%; Transporter classification TC:3.A.11.1.1. Codon Adaptation Index (CAI): 0.761. Curator(s): J. Alves; Protein involved in hydrolase activity.
   
  
 0.833
comEB
DCMP deaminase, putative; GC: 48.08%; Codon Adaptation Index (CAI): 0.761; Protein involved in hydrolase activity.
  
  
 0.824
comYC
Competence protein ComYC, putative; GC: 42.45%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.818. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.982); Curator(s): M. Serrano, J. Alves; Protein involved in type II protein secretion system.
   
  
 0.779
cinA
Competence-damage protein, putative; GC: 47.33%; Codon Adaptation Index (CAI): 0.77. Helix-turn-helix prediction: AraC; Protein involved in Mo-molybdopterin cofactor biosynthesis and establishment of competence for transformation; Belongs to the CinA family.
     
 0.779
holA
Conserved hypothetical protein; GC: 41.93%; Codon Adaptation Index (CAI): 0.805. Helix-turn-helix prediction: AraC. Curator(s): X. Ge; Protein involved in DNA replication.
 
   
 0.767
recA
RecA protein, putative; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.753
comYB
Competence protein ComYB, putative; GC: 44.18%; Transporter classification TC:3.A.14.1.1. Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.788. Curator(s): M. Serrano, J. Alves.
  
  
 0.742
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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