Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0718Conserved uncharacterized protein; GC: 41.64%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.823. Possibly membrane-associated, QG-rich protein. Curator(s): X. Ge. (364 aa)    
Predicted Functional Partners:
comEC
Competence protein, putative; GC: 43.24%; Transporter classification TC:3.A.11.1.1. Transmembrane domains: 9. Codon Adaptation Index (CAI): 0.763. Helix-turn-helix prediction: AraC. Curator(s): X. Ge, J. Alves; Protein involved in establishment of competence for transformation.
       0.706
comEA
DNA uptake protein, putative; GC: 46.11%; Transporter classification TC:3.A.11.1.1. Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.777. SignalP prediction: Yes (prob. 0.536); Curator(s): X. Ge, J. Alves; Protein involved in establishment of competence for transformation.
       0.619
holA
Conserved hypothetical protein; GC: 41.93%; Codon Adaptation Index (CAI): 0.805. Helix-turn-helix prediction: AraC. Curator(s): X. Ge; Protein involved in DNA replication.
       0.585
sodA
Mn/Fe-dependent superoxide dismutase, putative; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
       0.455
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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