Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argRTranscriptional repressor (arginine synthesis), putative; Regulates arginine biosynthesis genes. (156 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase, putative; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.787
argJ
Ornithine acetyltransferase / amino-acid acetyltransferase, putative; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
  
 0.785
queA
S-adenosylmethio nine:tRNA-ribosyltransferase-isomerase (queuine synthetase), putative; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
     
 0.770
arc
Ornithine carbamoyltransferase, catabolic, putative; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
  
 0.759
argG
Argininosuccinate synthase, putative; GC: 47.67%; Codon Adaptation Index (CAI): 0.765; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.749
SSA_0745
Hypothetical protein; GC: 39.19%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.744. Curator(s): X. Ge.
       0.736
argC
N-acetyl-gamma-glutamyl-phosphate reductase, putative; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.734
argH
Argininosuccinate lyase, putative; GC: 48.08%; Codon Adaptation Index (CAI): 0.781; Protein involved in lyase activity.
  
  
 0.724
nagB
Glucosamine-6-phosphate deaminase, putative; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.552
argD
Acetylornithine aminotransferase, putative; GC: 47.94%; Codon Adaptation Index (CAI): 0.776. Curator(s): X. Ge; Protein involved in pyridoxal phosphate binding; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
  
 0.545
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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