Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
SSA_0761Transcriptional regulator, XRE family, putative; GC: 48.36%; Codon Adaptation Index (CAI): 0.695. Curator(s): X. Ge, J. Alves; Protein involved in DNA binding. (70 aa)    
Predicted Functional Partners:
SSA_0762
Conserved hypothetical protein; GC: 36.34%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.754. SignalP prediction: Yes (prob. 0.813); Curator(s): X. Ge.
       0.726
SSA_0765
Conserved hypothetical protein; GC: 39.89%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.74. SignalP prediction: Yes (prob. 0.566); Curator(s): X. Ge; Protein involved in peptidase activity.
       0.692
SSA_0763
Transcription repressor, putative; GC: 42.54%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.779. Similar to negative regulator of Streptococcus sobrinus surface protein antigen gene. Curator(s): X. Ge, J. Alves.
       0.652
argC
N-acetyl-gamma-glutamyl-phosphate reductase, putative; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
       0.622
SSA_0766
Conserved hypothetical protein; GC: 39.45%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.775. SignalP prediction: Yes (prob. 0.469); Curator(s): X. Ge.
       0.619
argB
Acetylglutamate kinase, putative; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
       0.558
argJ
Ornithine acetyltransferase / amino-acid acetyltransferase, putative; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
       0.557
argD
Acetylornithine aminotransferase, putative; GC: 47.94%; Codon Adaptation Index (CAI): 0.776. Curator(s): X. Ge; Protein involved in pyridoxal phosphate binding; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
       0.546
SSA_2011
ABC-type multidrug transport system, ATPase component, putative; GC: 42.86%; Transporter classification TC:3.A.1.124.1. Codon Adaptation Index (CAI): 0.811. Curator(s): J. Alves; Protein involved in ATPase activity and nucleoside-triphosphatase activity.
       0.448
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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