STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0765Conserved hypothetical protein; GC: 39.89%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.74. SignalP prediction: Yes (prob. 0.566); Curator(s): X. Ge; Protein involved in peptidase activity. (233 aa)    
Predicted Functional Partners:
SSA_0762
Conserved hypothetical protein; GC: 36.34%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.754. SignalP prediction: Yes (prob. 0.813); Curator(s): X. Ge.
       0.805
SSA_0763
Transcription repressor, putative; GC: 42.54%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.779. Similar to negative regulator of Streptococcus sobrinus surface protein antigen gene. Curator(s): X. Ge, J. Alves.
       0.773
SSA_0766
Conserved hypothetical protein; GC: 39.45%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.775. SignalP prediction: Yes (prob. 0.469); Curator(s): X. Ge.
 
    
0.740
SSA_0761
Transcriptional regulator, XRE family, putative; GC: 48.36%; Codon Adaptation Index (CAI): 0.695. Curator(s): X. Ge, J. Alves; Protein involved in DNA binding.
       0.692
argC
N-acetyl-gamma-glutamyl-phosphate reductase, putative; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
       0.541
argJ
Ornithine acetyltransferase / amino-acid acetyltransferase, putative; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
    0.512
SSA_0193
CAAX amino terminal protease family protein, putative; GC: 39.23%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.758. SignalP prediction: Yes (prob. 0.652); Curator(s): M. Serrano, J. Alves.
  
     0.450
SSA_2077
Conserved hypothetical protein; GC: 35.09%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.776.
  
     0.450
argB
Acetylglutamate kinase, putative; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
       0.433
argD
Acetylornithine aminotransferase, putative; GC: 47.94%; Codon Adaptation Index (CAI): 0.776. Curator(s): X. Ge; Protein involved in pyridoxal phosphate binding; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
       0.425
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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