Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ptsHHistidine-containing phosphocarrier protein of the PTS, putative; GC: 41.67%; Transporter classification TC:8.A.8.1.1. Codon Adaptation Index (CAI): 0.817. Curator(s): X. Ge; Protein involved in transferase activity and phosphoenolpyruvate-dependent sugar phosphotransferase system. (87 aa)    
Predicted Functional Partners:
ptsI
PTS enzyme I, putative; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
fruA
PTS system, fructose specific II ABC components, putative; GC: 43.96%; Transporter classification TC:4.A.2.1.3. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.786.
 
 
 0.992
SSA_1918
Phosphotransferase system, mannose-specific EIIAB, putative; GC: 45.97%; Transporter classification TC:4.A.6.1.1. Codon Adaptation Index (CAI): 0.799; Protein involved in transferase activity.
  
 0.991
SSA_0379
PTS system, beta-glucoside-specific EII component, putative; GC: 44.98%; Transporter classification TC:4.A.1.2.6. Transmembrane domains: 11. Codon Adaptation Index (CAI): 0.805. Curator(s): T. Kitten.
  
 0.986
scrA
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific, putative; GC: 42.12%; Transporter classification TC:4.A.1.2.1. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.809. Curator(s): M. Chaplin.
  
 0.986
SSA_1752
Phosphotransferase system, trehalose-specific IIBC component, putative; GC: 44.53%; Transporter classification TC:4.A.1.2.4. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.774.
  
 0.986
SSA_0057
Phosphotransferase system sugar-specific EII component, putative; GC: 42.72%; Transporter classification TC:4.A.6.1.2. Codon Adaptation Index (CAI): 0.789. Curator(s): J. Alves; Protein involved in transferase activity.
 
 0.944
SSA_0219
PTS system, sugar-specific enzyme IIA component, putative; GC: 49.54%; Transporter classification TC:4.A.6.1.4. Codon Adaptation Index (CAI): 0.79. Curator(s): P. Manque; Protein involved in transferase activity.
  
 0.936
SSA_0269
Phosphotransferase system (PTS) cellobiose-specific component IIA, putative; GC: 44.34%; Transporter classification TC:4.A.3.2.2. Codon Adaptation Index (CAI): 0.8. Curator(s): P. Manque; Protein involved in transferase activity.
   
 0.930
SSA_0282
Phosphotransferase system (PTS), cellobiose-specific IIA component, putative; GC: 40.43%; Transporter classification TC:4.A.3.2.1. Codon Adaptation Index (CAI): 0.772. Helix-turn-helix prediction: AraC. Curator(s): P. Manque.
   
 0.930
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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