Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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glgAGlycogen synthase, putative; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (476 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme, putative; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.999
glgC
Glucose-1-phosphate adenylyltransferase, putative; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.999
glgD
Glycogen biosynthesis protein GlgD, putative; GC: 42.89%; Codon Adaptation Index (CAI): 0.775. Curator(s): X. Ge; Protein involved in nucleotidyltransferase activity.
 
 0.999
glgP
Glycogen phosphorylase, putative; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.978
malQ
4-alpha-glucanotransferase, putative; GC: 46.49%; Codon Adaptation Index (CAI): 0.81. Helix-turn-helix prediction: AraC; Protein involved in transferase activity.
 
 
 0.960
malP
Maltodextrin phosphorylase, putative; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.932
dexB
Neopullulanase, putative; GC: 41.71%; Codon Adaptation Index (CAI): 0.767. Curator(s): J. Alves; Protein involved in hydrolase activity, neopullulanase activity and carbohydrate metabolism; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.756
pulI
Pullulanase, putative; GC: 45.69%; Codon Adaptation Index (CAI): 0.782; Protein involved in carbohydrate binding, pullulanase activity and carbohydrate metabolism; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.722
pulA
Type II secretory pathway, pullulanase PulA glycosidase, putative; GC: 47.76%; Codon Adaptation Index (CAI): 0.759; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.716
SSA_0453
Type II secretory pathway, pullulanase PulA glycosidase, putative; GC: 45.19%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.777. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.999); Curator(s): M. Chaplin.
 
  
 0.704
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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