STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uncHProton-translocating ATPase, F1 sector, delta subunit, putative; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (178 aa)    
Predicted Functional Partners:
uncE
Proton-translocating ATPase, F0 sector, subunit c, putative; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 0.999
uncB
Proton-translocating ATPase, F0 sector, subunit a, putative; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
  
 0.999
uncF
Proton-translocating ATPase, F0 sector, subunit b, putative; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 0.999
uncA
Proton-translocating ATPase, F1 sector, alpha subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
  
 0.999
uncG
Proton-translocating ATPase, F1 sector, gamma subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
  
 0.999
uncD
Proton-translocating ATPase, F1 sector, beta subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
  
 0.999
uncC
Proton-translocating ATPase, F1 sector, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.999
ntpK
V-type sodium ATPase, subunit K, putative; GC: 48.33%; Transporter classification TC:3.A.2.2.2. Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.755. SignalP prediction: Yes (prob. 0.96); Curator(s): J. Alves; Protein involved in hydrogen-transporting ATPase activity, rotational mechanism; Belongs to the V-ATPase proteolipid subunit family.
  
 0.949
ppx
Inorganic pyrophosphatase/exopolyphosphatase, putative; GC: 44.02%; Codon Adaptation Index (CAI): 0.805. Curator(s): J. Alves.
     
 0.905
rplD
50S ribosomal protein L4, putative; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
  
 0.891
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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