STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
murAUDP-N-acetylglucosamine-like protein, putative; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (426 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylenolpyruvoylglucosamine reductase, putative; Cell wall formation.
 
  
 0.991
glmU
N-acetylglucosamine-1-phosphate uridyltransferase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repea [...]
 
  
 0.965
murC
UDP-N-acetylmuramate--L-alanine ligase, putative; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.923
murZ
Conserved uncharacterized protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
  
0.909
epsC
UDP-N-acetylglucosamine 2-epimerase, putative; GC: 44.73%; Codon Adaptation Index (CAI): 0.809. Curator(s): M. Serrano; Protein involved in isomerase activity and lipopolysaccharide biosynthesis; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
 
  0.907
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
   
 0.898
murF
D-Ala-D-Ala adding enzyme, putative; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.893
SSA_0792
Hypothetical protein; GC: 38.8%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.748. SignalP prediction: Yes (prob. 0.76); Curator(s): X. Ge.
       0.855
galU
Glucose-1-phosphate uridylyltransferase, putative; GC: 45.83%; Codon Adaptation Index (CAI): 0.796. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.993); Helix-turn-helix prediction: AraC; Protein involved in nucleotidyltransferase activity.
    
 0.826
ddlA
D-ala,D-ala ligase, putative; Cell wall formation.
 
  
 0.820
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.