Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_0792Hypothetical protein; GC: 38.8%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.748. SignalP prediction: Yes (prob. 0.76); Curator(s): X. Ge. (60 aa)    
Predicted Functional Partners:
murA
UDP-N-acetylglucosamine-like protein, putative; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.855
endA
DNA-entry nuclease, putative; GC: 49.94%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.757. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.969); Curator(s): X. Ge; Protein involved in endonuclease activity and establishment of competence for transformation.
       0.762
SSA_0790
Conserved hypothetical protein; GC: 35.93%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.789. Curator(s): X. Ge, J. Alves.
       0.727
uncD
Proton-translocating ATPase, F1 sector, beta subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
       0.630
uncC
Proton-translocating ATPase, F1 sector, epsilon subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.630
uncG
Proton-translocating ATPase, F1 sector, gamma subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
  
  
 0.627
uncA
Proton-translocating ATPase, F1 sector, alpha subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
  
    0.618
uncH
Proton-translocating ATPase, F1 sector, delta subunit, putative; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
  
    0.574
uncF
Proton-translocating ATPase, F0 sector, subunit b, putative; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
       0.552
uncB
Proton-translocating ATPase, F0 sector, subunit a, putative; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
       0.548
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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