Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0795Conserved hypothetical protein; GC: 39.34%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.787. Curator(s): X. Ge. (121 aa)    
Predicted Functional Partners:
SSA_0794
Zn-dependent protease, putative; GC: 47.22%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.753. SignalP prediction: Yes (prob. 0.542); Curator(s): X. Ge; Protein involved in hydrolase activity and proteolysis.
       0.855
uup
ABC-NBD transporters with duplicated ATPase domains, putative; GC: 50.74%; Transporter classification TC:3.A.1.120.1. Codon Adaptation Index (CAI): 0.763. Curator(s): X. Ge, J. Alves; Protein involved in nucleoside-triphosphatase activity.
       0.716
endA
DNA-entry nuclease, putative; GC: 49.94%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.757. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.969); Curator(s): X. Ge; Protein involved in endonuclease activity and establishment of competence for transformation.
       0.464
estA
Tributyrin esterase, putative; GC: 47.82%; Codon Adaptation Index (CAI): 0.781; Protein involved in catalytic activity.
       0.446
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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