Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0799Hypothetical protein; GC: 34.11%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.742. SignalP prediction: Yes (prob. 0.762); Curator(s): X. Ge. (85 aa)    
Predicted Functional Partners:
cobQ
Glutamine amidotransferase, putative; GC: 45.04%; Codon Adaptation Index (CAI): 0.762. Curator(s): X. Ge; Protein involved in cobalamin biosynthesis.
       0.824
SSA_0801
Mur ligase family protein, putative; GC: 47.02%; Codon Adaptation Index (CAI): 0.776. LipoP prediction: SpI. Helix-turn-helix prediction: AraC. Curator(s): X. Ge; Protein involved in ligase activity.
       0.824
dacA-2
Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
       0.532
SSA_0803
Conserved hypothetical protein; GC: 45.5%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.773. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): X. Ge.
       0.532
recJ
Single-stranded DNA-specific exonuclease, 5'-3', putative; GC: 46.24%; Codon Adaptation Index (CAI): 0.791. Helix-turn-helix prediction: AraC; Protein involved in 5'-3' exonuclease activity.
       0.449
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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