STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dacA-2Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (282 aa)    
Predicted Functional Partners:
glmM
Phosphoglucomutase/phosphomannomutase family protein, putative; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.991
SSA_0803
Conserved hypothetical protein; GC: 45.5%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.773. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): X. Ge.
  
  
 0.946
pgm
Phosphoglucomutase; GC: 44.5%; Codon Adaptation Index (CAI): 0.821. Helix-turn-helix prediction: AraC.
   
 
 0.777
SSA_0801
Mur ligase family protein, putative; GC: 47.02%; Codon Adaptation Index (CAI): 0.776. LipoP prediction: SpI. Helix-turn-helix prediction: AraC. Curator(s): X. Ge; Protein involved in ligase activity.
     
 0.703
cobQ
Glutamine amidotransferase, putative; GC: 45.04%; Codon Adaptation Index (CAI): 0.762. Curator(s): X. Ge; Protein involved in cobalamin biosynthesis.
       0.693
SSA_2358
Conserved hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
   
 0.691
SSA_1271
Conserved uncharacterized protein; GC: 46.15%; Codon Adaptation Index (CAI): 0.775; Protein involved in nucleic acid binding.
 
   
 0.612
mutS2
DNA mismatch repair protein, putative; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.554
SSA_0799
Hypothetical protein; GC: 34.11%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.742. SignalP prediction: Yes (prob. 0.762); Curator(s): X. Ge.
       0.532
SSA_1076
Conserved hypothetical protein; GC: 44.94%; Codon Adaptation Index (CAI): 0.778; Protein involved in hydrolase activity and fatty acid biosynthesis.
 
     0.450
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.