STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
glmMPhosphoglucomutase/phosphomannomutase family protein, putative; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (450 aa)    
Predicted Functional Partners:
dacA-2
Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.991
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing], putative; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.982
glmU
N-acetylglucosamine-1-phosphate uridyltransferase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repea [...]
 
 
 0.978
nagB
Glucosamine-6-phosphate deaminase, putative; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.963
nagA
N-acetylglucosamine-6-phosphate deacetylase, putative; GC: 48.7%; Codon Adaptation Index (CAI): 0.786; Protein involved in hydrolase activity.
     
 0.950
SSA_0803
Conserved hypothetical protein; GC: 45.5%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.773. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): X. Ge.
  
  
 0.824
galU
Glucose-1-phosphate uridylyltransferase, putative; GC: 45.83%; Codon Adaptation Index (CAI): 0.796. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.993); Helix-turn-helix prediction: AraC; Protein involved in nucleotidyltransferase activity.
    
 0.752
pgi
Glucose-6-phosphate isomerase, putative; GC: 41.79%; Codon Adaptation Index (CAI): 0.77; Belongs to the GPI family.
  
 
 0.743
SSA_0810
P-loop ATPase, putative; Displays ATPase and GTPase activities.
 
   
 0.695
papS
TRNA nucleotidyltransferase, putative; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
      0.693
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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