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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0806Conserved hypothetical protein; GC: 41.86%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.797. SignalP prediction: Yes (prob. 0.956); Curator(s): X. Ge, J. Alves. (42 aa)    
Predicted Functional Partners:
obg
GTP-binding protein, putative; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.660
SSA_0808
Conserved hypothetical protein; GC: 42.59%; Codon Adaptation Index (CAI): 0.748. Curator(s): X. Ge.
       0.646
SSA_0805
Collagen-binding surface protein, putative; GC: 41.74%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.794. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): X. Ge.
       0.505
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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