STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SSA_0841Hypothetical protein; GC: 40.09%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.712. SignalP prediction: Yes (prob. 0.619); Curator(s): L. Ozaki. (73 aa)    
Predicted Functional Partners:
gtfA-2
Glucosyltransferase, putative; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.
     
 0.838
SSA_0839
Conserved hypothetical protein; GC: 40.44%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.784. Curator(s): L. Ozaki.
     
 0.801
gtfB
GtfB, putative; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
     
 0.787
SSA_0835
Accessory secretory protein Asp3, putative; GC: 43.12%; Transporter classification TC:3.A.5.10.1. Codon Adaptation Index (CAI): 0.758. Curator(s): L. Ozaki.
     
 0.764
SSA_0834
Accessory secretory protein Asp2, putative; GC: 47.32%; Transporter classification TC:3.A.5.10.1. Codon Adaptation Index (CAI): 0.788. Curator(s): L. Ozaki.
     
 0.761
SSA_0833
Accessory secretory protein Asp1, putative; GC: 47.44%; Transporter classification TC:3.A.5.10.1. Codon Adaptation Index (CAI): 0.781. Curator(s): L. Ozaki.
     
 0.760
secA2
SecA-like protein, putative; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
       0.746
secY2
SecY-like protein, putative; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
     
 0.741
SSA_0831
Nucleotide sugar synthetase-like protein, putative; GC: 49.65%; Codon Adaptation Index (CAI): 0.782. Curator(s): L. Ozaki.
     
 0.658
SSA_0830
Glycosyltransferase, putative; GC: 46.76%; Codon Adaptation Index (CAI): 0.787. Curator(s): L. Ozaki; Protein involved in transferase activity, transferring hexosyl groups.
     
 0.641
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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