Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rmlDDTDP-L-rhamnose synthase, putative; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (284 aa)    
Predicted Functional Partners:
rmlC
DTDP-4-keto-6-deoxyglucose-3,5-epimerase, putative; GC: 45.12%; Codon Adaptation Index (CAI): 0.782; Protein involved in isomerase activity and lipopolysaccharide biosynthesis.
 
 0.999
rmlB
DTDP-glucose-4,6-dehydratase, putative; GC: 45.46%; Codon Adaptation Index (CAI): 0.79; Protein involved in NAD binding and nucleotide-sugar metabolism; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
 0.997
rmlA
Glucose-1-phosphate thymidylytransferase, putative; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
  
 0.991
rgpA
Rhamnosyltransferase, putative; GC: 43.69%; Codon Adaptation Index (CAI): 0.79; Protein involved in transferase activity.
 
  
 0.740
rgpB
Polysaccharide biosynthesis protein/ rhamnosyltransferase, putative; GC: 45.19%; Codon Adaptation Index (CAI): 0.792; Protein involved in transferase activity.
 
  
 0.736
galE1
DTDP-4-dehydrorhamnose 3,5-epimerase, putative; GC: 43.99%; Codon Adaptation Index (CAI): 0.795.
  
 0.696
gtrB
Glycosyltransferase (vectorial glycosyl polymerization (VGP) family), putative; GC: 45.52%; Transporter classification TC:9.B.32.1.3. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.773. Curator(s): L. Ozaki; Protein involved in transferase activity.
  
  
 0.685
SSA_0857
Conserved hypothetical protein; GC: 37.09%; Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.756. Curator(s): L. Ozaki, J. Alves; Protein involved in transferase activity.
 
     0.655
rgpFc
Lipopolysaccharide biosynthesis protein, putative; GC: 41.77%; Codon Adaptation Index (CAI): 0.777; Protein involved in transferase activity.
  
  
 0.644
SSA_2213
Nucleotide sugar dehydratase, putative; GC: 43.19%; Codon Adaptation Index (CAI): 0.77; Protein involved in oxidoreductase activity.
 
 
 0.612
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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