Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsXCell division protein FtsX, putative; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (308 aa)    
Predicted Functional Partners:
ftsE
Cell division protein FtsE, putative; Part of the ABC transporter FtsEX involved in cellular division.
 
 
 0.999
pcsB
Secreted antigen GbpB/SagA; GC: 42.63%; Codon Adaptation Index (CAI): 0.794. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves.
 
  
 0.805
prfB
Peptide chain release factor 2, putative; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
     
 0.792
SSA_0164
Conserved hypothetical protein; GC: 45.49%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.777. SignalP prediction: Yes (prob. 0.993); Curator(s): M. Serrano, J. Alves; possible function in cell wall glycoprotein metabolism.
   
 
 0.771
SSA_1019
Collagen-binding surface protein, putative; GC: 42.42%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.8. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1).
    
 
 0.761
ftsW
Cell division protein FtsW, putative; GC: 44.2%; Transporter classification TC:9.B.3.1.3. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.729. SignalP prediction: Yes (prob. 0.95); Protein involved in cell division; Belongs to the SEDS family.
  
  
 0.691
ftsZ
Cell division protein FtsZ, putative; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.678
ftsA
Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
 
 0.649
sepF
Conserved uncharacterized protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
      
 0.601
divIVA
Cell division protein DivIVA, putative; GC: 43.77%; Codon Adaptation Index (CAI): 0.813. Curator(s): P. Xu; Protein involved in cell division.
  
   
 0.524
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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