STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
grkGlycerate kinase, putative; GC: 49.78%; Codon Adaptation Index (CAI): 0.752. Curator(s): L. Ozaki; Protein involved in organic acid phosphorylation; Belongs to the glycerate kinase type-1 family. (372 aa)    
Predicted Functional Partners:
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, putative; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.901
serB
Phosphoserine phosphatase, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.765. Curator(s): L. Ozaki; Protein involved in phosphoric monoester hydrolase activity.
       0.849
tadA
Conserved hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
      0.679
SSA_0881
Hypothetical protein; GC: 31.83%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.734. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.942); Curator(s): L. Ozaki.
       0.652
ezrA
Cell division regulator, negative regulator of FtsZ septation ring formation, putative; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
       0.570
birA
Biotin--[acetyl-CoA-carboxylase] ligase, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.512
gldA
Glycerol dehydrogenase, NAD+ dependent, putative; GC: 45.57%; Codon Adaptation Index (CAI): 0.778. Curator(s): P. Manque; Protein involved in oxidoreductase activity.
      
 0.504
trpA
Tryptophan synthase alpha chain, putative; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
      
 0.502
SSA_0880
Hypothetical protein; GC: 31.56%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.765. SignalP prediction: Yes (prob. 0.619); Curator(s): L. Ozaki.
       0.480
glyA
Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      
 0.473
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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