STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0896Two-component system, OmpR family, response regulator Irr; GC: 45.36%; Codon Adaptation Index (CAI): 0.8. Curator(s): L. Ozaki, J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent. (218 aa)    
Predicted Functional Partners:
SSA_0897
Two component system histidine kinase, putative; GC: 45.27%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.78. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.982); Curator(s): L. Ozaki; Protein involved in transferase activity, transferring phosphorus-containing groups.
 
 0.998
SSA_1114
Histidine kinase, putative; GC: 40.77%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.747. SignalP prediction: Yes (prob. 0.727); Protein involved in transferase activity, transferring phosphorus-containing groups.
 
 
 0.838
nisK
NisK (sensor-receptor histidine kinase domain), putative; GC: 42.58%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.784. Curator(s): P. Manque, J. Alves; Protein involved in transferase activity, kinase activity and transferase activity, transferring phosphorus-containing groups.
 
 
 0.832
ciaH
Sensor protein ciaH, putative; GC: 41.74%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.823. Curator(s): T. Kitten; Protein involved in transferase activity, transferring phosphorus-containing groups and establishment of competence for transformation.
 
 
 0.827
SSA_0895
ATP-binding cassette transporter-like protein, putative; GC: 45.32%; Transporter classification TC:3.A.1.122.1. Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.778. SignalP prediction: Yes (prob. 0.46); Curator(s): L. Ozaki.
       0.809
SSA_0402
Histidine kinase, putative; GC: 48.4%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.769. SignalP prediction: Yes (prob. 0.46); Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in transferase activity, transferring phosphorus-containing groups and kinase activity.
 
 
 0.804
SSA_1564
Histidine kinase, putative; GC: 44.96%; Transporter classification TC:2.A.21.9.1. Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.774; Protein involved in transferase activity, transferring phosphorus-containing groups.
 
 
 0.802
SSA_0893
ATP-binding cassette transporter-like protein, putative; GC: 44.55%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.805. LipoP prediction: SpII. SignalP prediction: Yes (prob. 0.943); Curator(s): L. Ozaki.
     
 0.793
SSA_0894
ATP-binding cassette protein, putative; GC: 47.11%; Transporter classification TC:3.A.1.122.1. Codon Adaptation Index (CAI): 0.767. Curator(s): L. Ozaki; Protein involved in nucleoside-triphosphatase activity.
       0.793
SSA_0892
ATP-binding cassette lipoprotein, putative; GC: 41.76%; Codon Adaptation Index (CAI): 0.77. LipoP prediction: SpII. SignalP prediction: Yes (prob. 0.879); Curator(s): L. Ozaki; Protein involved in ATP binding.
       0.734
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.