Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0909Transcriptional regulator, AbrB family (stationary/sporulation gene expression), putative; GC: 43.75%; Codon Adaptation Index (CAI): 0.78. Curator(s): T. Kitten, J. Alves. (63 aa)    
Predicted Functional Partners:
SSA_0911
Membrane protein, putative; GC: 42.11%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.767. SignalP prediction: Yes (prob. 0.557); Curator(s): T. Kitten; Protein involved in ATPase activity, coupled to transmembrane movement of substances.
 
     0.866
SSA_0910
ABC-type multidrug transporter, ATPase component, putative; GC: 46.56%; Transporter classification TC:3.A.1.105.2. Codon Adaptation Index (CAI): 0.777. Curator(s): T. Kitten, J. Alves; Protein involved in nucleoside-triphosphatase activity.
 
     0.593
SSA_2132
Ure cluster protein, putative; GC: 45.69%; Transmembrane domains: 11. Codon Adaptation Index (CAI): 0.726. Helix-turn-helix prediction: AraC.
  
     0.556
SSA_0908
ABC-type uncharacterized transport system, periplasmic component, putative; GC: 44.25%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.809. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.999); Curator(s): T. Kitten, J. Alves.
       0.455
doc
Prophage maintenance system killer protein (DOC: death-on-curing), putative; GC: 30.39%; Codon Adaptation Index (CAI): 0.762. Curator(s): T. Kitten, J. Alves.
     
 0.441
SSA_1313
Conserved hypothetical protein; GC: 44.6%; Codon Adaptation Index (CAI): 0.752. Helix-turn-helix prediction: AraC; Protein involved in regulation of transcription.
  
     0.435
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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