STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arsCArsenate reductase, glutaredoxin family, putative; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. (133 aa)    
Predicted Functional Partners:
suhB
Inositol monophosphatase (Mg++ dependent), putative; GC: 46.69%; Codon Adaptation Index (CAI): 0.769. Curator(s): T. Kitten, J. Alves; Protein involved in inositol or phosphatidylinositol phosphatase activity.
 
     0.872
SSA_0940
NOL1/NOP2/sun family protein, putative; GC: 46.36%; Codon Adaptation Index (CAI): 0.798. Curator(s): T. Kitten; Protein involved in transferase activity.
  
    0.858
SSA_0938
Conserved hypothetical protein; GC: 40.86%; Codon Adaptation Index (CAI): 0.774. Curator(s): T. Kitten; Protein involved in molecular function unknown; Belongs to the UPF0223 family.
       0.855
rpoA
DNA-directed RNA polymerase, alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.847
mreA
FAD synthase, putative; GC: 46.2%; Codon Adaptation Index (CAI): 0.793. Curator(s): T. Kitten; Protein involved in riboflavin biosynthesis; Belongs to the ribF family.
  
  
 0.720
clpP
ATP-dependent Clp protease, proteolytic subunit, putative; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
      
 0.719
clpX
ATP-dependent Clp protease ATP-binding subunit clpX, putative; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
  
 0.714
nox
H2O-forming NADH dehydrogenase, putative; GC: 40.38%; Codon Adaptation Index (CAI): 0.812. Curator(s): J. Alves.
      
 0.710
pstS
ABC-type phosphate transport system, periplasmic component, putative; GC: 45.42%; Transporter classification TC:3.A.1.7.1. Codon Adaptation Index (CAI): 0.781. Curator(s): T. Kitten; Protein involved in transport.
     
 0.706
pstC1
ABC transporter membrane-spanning permease-phosphate transport, putative; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
       0.691
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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