Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_0938Conserved hypothetical protein; GC: 40.86%; Codon Adaptation Index (CAI): 0.774. Curator(s): T. Kitten; Protein involved in molecular function unknown; Belongs to the UPF0223 family. (92 aa)    
Predicted Functional Partners:
suhB
Inositol monophosphatase (Mg++ dependent), putative; GC: 46.69%; Codon Adaptation Index (CAI): 0.769. Curator(s): T. Kitten, J. Alves; Protein involved in inositol or phosphatidylinositol phosphatase activity.
 
  
 0.960
arsC
Arsenate reductase, glutaredoxin family, putative; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
       0.855
SSA_0940
NOL1/NOP2/sun family protein, putative; GC: 46.36%; Codon Adaptation Index (CAI): 0.798. Curator(s): T. Kitten; Protein involved in transferase activity.
       0.855
pstS
ABC-type phosphate transport system, periplasmic component, putative; GC: 45.42%; Transporter classification TC:3.A.1.7.1. Codon Adaptation Index (CAI): 0.781. Curator(s): T. Kitten; Protein involved in transport.
       0.706
pstC1
ABC transporter membrane-spanning permease-phosphate transport, putative; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
       0.706
pstC
ABC transporter membrane-spanning permease-phosphate transport, putative; GC: 46.33%; Transporter classification TC:3.A.1.7.1. Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.777. Curator(s): T. Kitten.
       0.706
pstB2
Phosphate import ATP-binding protein pstB 2, putative; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
       0.701
mreA
FAD synthase, putative; GC: 46.2%; Codon Adaptation Index (CAI): 0.793. Curator(s): T. Kitten; Protein involved in riboflavin biosynthesis; Belongs to the ribF family.
       0.672
gpsB
Conserved DivIVA-like protein, putative; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
     0.657
pstB1
Phosphate import ATP-binding protein pstB 1, putative; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
       0.641
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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