Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepNAminopeptidase N, putative; GC: 45.38%; Codon Adaptation Index (CAI): 0.804. Curator(s): T. Kitten. (846 aa)    
Predicted Functional Partners:
gshAB
Glutathione biosynthesis bifunctional protein gshAB (Gamma-GCS-GS) (GCS-GS), putative; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
   
 
 0.910
glyA
Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.885
pepXP
Xaa-Pro dipeptidyl-peptidase, putative; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
 
   
 0.874
cysK
Cysteine synthase, putative; GC: 47.42%; Codon Adaptation Index (CAI): 0.797; Protein involved in lyase activity and cysteine biosynthesis; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.811
SSA_0042
Amino acid recemase, putative; GC: 44.06%; Codon Adaptation Index (CAI): 0.766. Curator(s): J. Alves; Protein involved in aspartate racemase activity and racemase and epimerase activity, acting on amino acids and derivatives; Belongs to the aspartate/glutamate racemases family.
     
  0.800
pepP
GC: 46.8%; Codon Adaptation Index (CAI): 0.768. Curator(s): M. Chaplin; Protein involved in hydrolase activity; Belongs to the peptidase M24B family.
  
 
 0.800
SSA_1736
L-cysteine desulfhydrase, putative; GC: 45.5%; Codon Adaptation Index (CAI): 0.794; Protein involved in 1-aminocyclopropane-1-carboxylate synthase activity.
     
  0.800
pepQ
Proline dipeptidase, putative; GC: 46.17%; Codon Adaptation Index (CAI): 0.806; Protein involved in metalloexopeptidase activity and dipeptidase activity.
  
 
 0.755
pepO
Zinc metalloproteinase in scaA 5'region, putative; GC: 48.44%; Codon Adaptation Index (CAI): 0.785. Curator(s): P. Manque; Protein involved in metal ion binding and hydrolase activity.
 
   
 0.701
pepV
Dipeptidase V, putative; GC: 43.62%; Codon Adaptation Index (CAI): 0.789; Protein involved in metallopeptidase activity.
  
 
 0.684
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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