STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0961Possible ketopantoate reductase PanE/ApbA, putative; GC: 39.3%; Codon Adaptation Index (CAI): 0.777. Curator(s): T. Kitten; Protein involved in 2-dehydropantoate 2-reductase activity. (312 aa)    
Predicted Functional Partners:
ciaR
Two-component system, OmpR family, response regulator CiaR; GC: 40.59%; Codon Adaptation Index (CAI): 0.791. Curator(s): T. Kitten, J. Alves; Protein involved in sensory perception and establishment of competence for transformation.
       0.739
ciaH
Sensor protein ciaH, putative; GC: 41.74%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.823. Curator(s): T. Kitten; Protein involved in transferase activity, transferring phosphorus-containing groups and establishment of competence for transformation.
       0.739
folK
Bifunctional folate synthesis protein, putative; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.575
birA
Biotin--[acetyl-CoA-carboxylase] ligase, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.551
lguL
Lactoylglutathione lyase, putative; GC: 43.67%; Codon Adaptation Index (CAI): 0.829. Curator(s): T. Kitten; Protein involved in oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, lyase activity and carbohydrate metabolism.
       0.509
SSA_0958
Hypothetical protein; GC: 47.53%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.786. Curator(s): T. Kitten.
       0.494
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit, putative; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
     
 0.454
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit, putative; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.450
SSA_0963
Peptidoglycan N-acetylglucosamine deacetylase A, putative; GC: 45.35%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.786. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten; Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds.
  
    0.418
SSA_0607
ABC transporter, permease component, putative; GC: 46.94%; Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.754. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.999); Curator(s): D. Akan, J. Alves.
  
     0.411
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.