STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0983Conserved uncharacterized protein; GC: 46.92%; Codon Adaptation Index (CAI): 0.835. Curator(s): T. Kitten; Belongs to the SUA5 family. (259 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase small subunit, putative; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
     0.780
leuB
3-isopropylmalate dehydrogenase, putative; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family.
 
     0.762
leuC
3-isopropylmalate dehydratase large subunit, putative; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
     0.760
SSA_0978
Conserved hypothetical protein; GC: 43.45%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.724. Curator(s): T. Kitten.
       0.721
leuA
2-isopropylmalate synthase, putative; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
     
 0.655
SSA_1064
Conserved hypothetical protein; GC: 40.49%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.761. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves; (contains glucan-binding domain); Protein involved in dextransucrase activity.
  
     0.477
SSA_1914
Conserved hypothetical protein; GC: 38.8%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.82.
  
     0.461
SSA_0984
SlyA-like protein, putative; GC: 41.32%; Codon Adaptation Index (CAI): 0.825. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in regulation of transcription, DNA-dependent.
       0.459
SSA_0985
Conserved hypothetical protein; GC: 43.79%; Codon Adaptation Index (CAI): 0.776. Curator(s): T. Kitten.
       0.450
proW
ABC-type choline transporter, membrane-spanning permease, putative; GC: 43.98%; Transporter classification TC:3.A.1.12.4. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.771. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten.
       0.449
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.