STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
galRGalactose operon transcriptional repressor, LacI family, putative; GC: 47.31%; Codon Adaptation Index (CAI): 0.757. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten, J. Alves; Protein involved in regulation of transcription, DNA-dependent. (333 aa)    
Predicted Functional Partners:
galK
Galactokinase, putative; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.966
galT
Galactose-1-phosphate-uridylyltransferase, putative; GC: 48.52%; Codon Adaptation Index (CAI): 0.774.
 
  
 0.874
birA
Biotin--[acetyl-CoA-carboxylase] ligase, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.872
SSA_2087
Conserved uncharacterized protein; GC: 44.11%; Codon Adaptation Index (CAI): 0.734. Helix-turn-helix prediction: AraC.
  
     0.766
galM
Aldose 1-epimerase, putative; Converts alpha-aldose to the beta-anomer.
 
   
 0.727
galE
UDP-glucose 4-epimerase, putative; GC: 47.8%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.782; Protein involved in NAD binding; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.706
ptsH
Histidine-containing phosphocarrier protein of the PTS, putative; GC: 41.67%; Transporter classification TC:8.A.8.1.1. Codon Adaptation Index (CAI): 0.817. Curator(s): X. Ge; Protein involved in transferase activity and phosphoenolpyruvate-dependent sugar phosphotransferase system.
   
 
 0.668
fruA
PTS system, fructose specific II ABC components, putative; GC: 43.96%; Transporter classification TC:4.A.2.1.3. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.786.
     
 0.631
msmR
Arabinose (multiple sugar metabolism) operon transcriptional regulator, putative; GC: 41.01%; Codon Adaptation Index (CAI): 0.746. Helix-turn-helix prediction: AraC; Protein involved in regulation of transcription and regulation of transcription, DNA-dependent.
 
    0.627
SSA_1165
Transcriptional regulator, GntR family, putative; GC: 46.78%; Codon Adaptation Index (CAI): 0.775. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in regulation of transcription.
  
   
 0.569
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.