Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
msmRArabinose (multiple sugar metabolism) operon transcriptional regulator, putative; GC: 41.01%; Codon Adaptation Index (CAI): 0.746. Helix-turn-helix prediction: AraC; Protein involved in regulation of transcription and regulation of transcription, DNA-dependent. (290 aa)    
Predicted Functional Partners:
SSA_0594
Transcriptional regulator, AraC family, putative; GC: 43.66%; Codon Adaptation Index (CAI): 0.78. Helix-turn-helix prediction: AraC. Curator(s): D. Akan, J. Alves; Protein involved in regulation of transcription and regulation of transcription, DNA-dependent.
  
     0.753
SSA_1002
Alpha-galactosidase, putative; GC: 42.39%; Codon Adaptation Index (CAI): 0.767; Protein involved in carbohydrate metabolism.
 
     0.737
SSA_1003
ABC transporter substrate-binding protein-multiple sugars, putative; GC: 42.54%; Transporter classification TC:3.A.1.1.2. Codon Adaptation Index (CAI): 0.784. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Protein involved in transport.
 
   
 0.699
galR
Galactose operon transcriptional repressor, LacI family, putative; GC: 47.31%; Codon Adaptation Index (CAI): 0.757. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten, J. Alves; Protein involved in regulation of transcription, DNA-dependent.
 
    0.627
msmF
ABC transporter membrane-spanning permease-multiple sugars, putative; GC: 41.98%; Transporter classification TC:3.A.1.1.2. Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.743. SignalP prediction: Yes (prob. 0.537).
 
   
 0.605
msmG
Sugar ABC transporter, permease protein, putative; GC: 37.65%; Transporter classification TC:3.A.1.1.2. Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.788. SignalP prediction: Yes (prob. 0.929).
 
   
 0.593
birA
Biotin--[acetyl-CoA-carboxylase] ligase, putative; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.578
gtfA
Dextransucrase, putative; GC: 41.84%; Codon Adaptation Index (CAI): 0.798; Protein involved in transferase activity, transferring glycosyl groups, dextransucrase activity and carbohydrate metabolism.
 
     0.442
SSA_0419
Alpha-galactosidase, putative; GC: 49.46%; Codon Adaptation Index (CAI): 0.77. Curator(s): M. Chaplin; Protein involved in hydrolase activity, acting on glycosyl bonds and carbohydrate metabolism.
 
     0.438
hslO
33 kDa chaperonin, putative; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
      
 0.414
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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