Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1018Zinc metalloprotease zmpC precursor, putative; GC: 45.25%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.781. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in metal ion binding. (3047 aa)    
Predicted Functional Partners:
SSA_0146
DNA repair ATPase, putative; GC: 44.57%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.772. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Possible ATPase involved in DNA repair, contains Gram-positive anchor. Curator(s): M. Serrano, J. Alves.
 
   0.728
SSA_2149
Conserved hypothetical protein; GC: 36.94%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.757. SignalP prediction: Yes (prob. 0.721).
  
     0.696
SSA_0722
Conserved hypothetical protein; GC: 42.29%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.777. Curator(s): X. Ge, J. Alves; possible membrane-associated peptidase; Protein involved in proteolysis.
  
     0.654
SSA_1181
Hydrolase, alpha/beta superfamily, putative; GC: 43.39%; Codon Adaptation Index (CAI): 0.797; Protein involved in catalytic activity.
  
     0.609
SSA_1019
Collagen-binding surface protein, putative; GC: 42.42%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.8. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1).
 
     0.592
SSA_1816
Conserved hypothetical protein; GC: 34.25%; Codon Adaptation Index (CAI): 0.751.
  
     0.579
crpA
CshA-like fibrillar surface protein A; GC: 46.68%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.801. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): L. Ozaki, J. Alves; Protein involved in calcium ion binding and pathogenesis.
 
    0.557
crpB
CshA-like fibrillar surface protein B; GC: 46.38%; Codon Adaptation Index (CAI): 0.797. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in pathogenesis.
 
    0.551
crpC
CshA-like fibrillar surface protein C; GC: 46.28%; Codon Adaptation Index (CAI): 0.794. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in pathogenesis.
 
    0.549
SSA_1535
Conserved hypothetical protein; GC: 45.49%; Codon Adaptation Index (CAI): 0.786.
  
     0.541
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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