Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
pdpPyrimidine nucleoside phosphorylase, putative; GC: 44.37%; Codon Adaptation Index (CAI): 0.805; Protein involved in transferase activity, transferring glycosyl groups. (425 aa)    
Predicted Functional Partners:
cdd
Cytidine deaminase, putative; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
 0.993
deoC
Deoxyribose-phosphate aldolase, putative; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 
 0.971
deoB
Phosphopentomutase, putative; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.971
udK
Uridine kinase, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.798. Curator(s): T. Kitten; Protein involved in transferase activity.
    
 0.968
tdk
Thymidine kinase, putative; GC: 43.8%; Codon Adaptation Index (CAI): 0.819.
    
 0.951
SSA_0105
Uridine kinase, putative; GC: 47.26%; Codon Adaptation Index (CAI): 0.723. Curator(s): M. Serrano; Protein involved in transferase activity.
    
 0.936
upp
Uracil phosphoribosyltransferase, putative; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
 0.929
pyrR
Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.915
YfkN
Cyclo-nucleotide phosphodiesterase, putative; GC: 48.96%; Codon Adaptation Index (CAI): 0.761. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): P. Manque; Protein involved in hydrolase activity, acting on ester bonds.
     
  0.900
SSA_1311
Hydrolase, haloacid dehalogenase-like family, putative; GC: 45.83%; Codon Adaptation Index (CAI): 0.773; Protein involved in hydrolase activity and metal ion binding.
     
  0.900
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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