Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_1053Pyruvate phosphate dikinase, putative; GC: 47.56%; Transporter classification TC:8.A.7.1.1. Codon Adaptation Index (CAI): 0.775. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in pyruvate, phosphate dikinase activity. (873 aa)    
Predicted Functional Partners:
ldh
L-lactate dehydrogenase, putative; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.913
eno
Enolase, putative; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.908
pykF
Pyruvate kinase I, fructose-stimulated, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.802. Curator(s): L. Ozaki; Protein involved in transferase activity and glycolysis; Belongs to the pyruvate kinase family.
     
 0.906
ppc
Phosphoenolpyruvate carboxylase, putative; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.906
SSA_0342
Pyruvate formate-lyase, putative; GC: 44.39%; Codon Adaptation Index (CAI): 0.783. Curator(s): T. Kitten; Protein involved in formate C-acetyltransferase activity and lyase activity.
    
 0.904
spxB
Pyruvate oxidase, putative; GC: 43.3%; Codon Adaptation Index (CAI): 0.777. Curator(s): T. Kitten; Protein involved in thiamin pyrophosphate binding; Belongs to the TPP enzyme family.
    
 0.904
acoB
Acetoin dehydrogenase, E1 component, beta subunit, putative; GC: 46.96%; Codon Adaptation Index (CAI): 0.795; Protein involved in acetoin dehydrogenase activity.
    
 0.904
acoA
Acetoin dehydrogenase, E1 component, alpha subunit, putative; GC: 44.58%; Codon Adaptation Index (CAI): 0.787; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor and acetoin dehydrogenase activity.
    
 0.904
SSA_1055
Conserved uncharacterized protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.901
pgk
Phosphoglycerate kinase, putative; GC: 43.27%; Codon Adaptation Index (CAI): 0.793. Curator(s): P. Manque; Protein involved in transferase activity; Belongs to the phosphoglycerate kinase family.
    
 0.821
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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