STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lspALipoprotein signal peptidase, putative; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (155 aa)    
Predicted Functional Partners:
lgt
Prolipoprotein diacylglyceryl transferase, putative; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
   
 0.933
SSA_1070
Ribosomal large subunit pseudouridine synthase D, putative; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.908
SSA_1068
Transcriptional regulator, LysR family (capsular polysaccharide biosynthesis regulation), putative; GC: 44.27%; Codon Adaptation Index (CAI): 0.802. Helix-turn-helix prediction: LysR. Curator(s): J. Alves; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family.
       0.855
eep
Zinc metalloprotease, putative; GC: 47.33%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.763; Protein involved in metal ion binding.
   
  
 0.699
SSA_1067
Conserved hypothetical protein; GC: 43.25%; Codon Adaptation Index (CAI): 0.766; Protein involved in N-acetyltransferase activity and transferase activity.
       0.695
proB
Glutamate 5-kinase, putative; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
  
    0.692
fruA
PTS system, fructose specific II ABC components, putative; GC: 43.96%; Transporter classification TC:4.A.2.1.3. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.786.
     
 0.692
ileS
Isoleucyl-tRNA synthetase, putative; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
  
  
 0.637
proA
Gamma-glutamyl phosphate reductase, putative; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.604
proC
Pyrroline-5-carboxylate reductase, putative; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.604
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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