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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1114Histidine kinase, putative; GC: 40.77%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.747. SignalP prediction: Yes (prob. 0.727); Protein involved in transferase activity, transferring phosphorus-containing groups. (344 aa)    
Predicted Functional Partners:
SSA_1113
Two-component system, OmpR family, response regulator SaeR; GC: 41.2%; Codon Adaptation Index (CAI): 0.77. Curator(s): J. Alves; Protein involved in sensory perception.
 0.996
nisR
Nisin biosynthesis two-component response transcriptional regulator nisR, putative; GC: 44.35%; Codon Adaptation Index (CAI): 0.765. Curator(s): P. Manque, J. Alves; Protein involved in sensory perception.
 
 0.882
SSA_0896
Two-component system, OmpR family, response regulator Irr; GC: 45.36%; Codon Adaptation Index (CAI): 0.8. Curator(s): L. Ozaki, J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
 0.862
SSA_1565
Two-component system, OmpR family, response regulator VicR; GC: 45.58%; Codon Adaptation Index (CAI): 0.814. Curator(s): J. Alves; Protein involved in sensory perception.
 
 0.862
SSA_0401
Two-component response transcriptional regulator; GC: 48.75%; Codon Adaptation Index (CAI): 0.789. Curator(s): T. Kitten, J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
 0.858
SSA_1794
Two-component system, OmpR family, manganese sensing response regulator; GC: 48.37%; Codon Adaptation Index (CAI): 0.795. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in sensory perception.
 
 0.848
SSA_1685
Two-component response transcriptional regulator; GC: 45.71%; Codon Adaptation Index (CAI): 0.762. Curator(s): J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
 0.836
ciaR
Two-component system, OmpR family, response regulator CiaR; GC: 40.59%; Codon Adaptation Index (CAI): 0.791. Curator(s): T. Kitten, J. Alves; Protein involved in sensory perception and establishment of competence for transformation.
 
 0.831
csrR
Two-component response transcriptional regulator; GC: 45.51%; Codon Adaptation Index (CAI): 0.8. Curator(s): J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
 
 0.777
SSA_0402
Histidine kinase, putative; GC: 48.4%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.769. SignalP prediction: Yes (prob. 0.46); Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in transferase activity, transferring phosphorus-containing groups and kinase activity.
 
 
 0.744
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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