Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_1122Thioredoxin family protein, putative; GC: 43.06%; Codon Adaptation Index (CAI): 0.801. LipoP prediction: SpII. SignalP prediction: Yes (prob. 0.998); Protein involved in electron carrier activity. (191 aa)    
Predicted Functional Partners:
SSA_1121
Cytochrome C-type biogenesis protein, putative; GC: 41.53%; Transporter classification TC:5.A.1.2.1. Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.78; Protein involved in cytochrome complex assembly.
  
 0.990
SSA_1115
Cytochrome C-type biogenesis protein, putative; GC: 43.88%; Transporter classification TC:5.A.1.2.1. Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.744. SignalP prediction: Yes (prob. 0.5); Protein involved in cytochrome complex assembly.
  
 0.958
tmk
Thymidylate kinase, putative; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.724
SSA_1119
Two-component response transcriptional regulator; GC: 42.04%; Codon Adaptation Index (CAI): 0.771. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in regulation of transcription and regulation of transcription, DNA-dependent.
 
   
 0.638
SSA_1120
Two-component sensor kinase (with C-terminal ATPase domain), putative; GC: 44.25%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.793. SignalP prediction: Yes (prob. 0.513); Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in kinase activity and transferase activity.
 
   
 0.636
msrA
Peptide methionine sulfoxide reductase, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
  
 0.613
msrB
Peptide methionine sulfoxide reductase msrA/msrB, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.411
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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