Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
noxH2O-forming NADH dehydrogenase, putative; GC: 40.38%; Codon Adaptation Index (CAI): 0.812. Curator(s): J. Alves. (458 aa)    
Predicted Functional Partners:
SSA_1415
Oxidoreductase, putative; GC: 49.41%; Codon Adaptation Index (CAI): 0.769. LipoP prediction: SpI; Protein involved in oxidoreductase activity.
  
 
 0.853
sodA
Mn/Fe-dependent superoxide dismutase, putative; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.749
tpx
Thiol peroxidase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
      
 0.738
apbE
Thiamine biosynthesis lipoprotein, putative; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
     
 0.725
arsC
Arsenate reductase, glutaredoxin family, putative; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
      
 0.710
SSA_1128
Voltage gated chloride channel EriC, putative; GC: 46.11%; Transporter classification TC:1.A.11.5.1. Transmembrane domains: 11. Codon Adaptation Index (CAI): 0.775. Curator(s): J. Alves.
 
   
 0.695
SSA_0342
Pyruvate formate-lyase, putative; GC: 44.39%; Codon Adaptation Index (CAI): 0.783. Curator(s): T. Kitten; Protein involved in formate C-acetyltransferase activity and lyase activity.
   
  
 0.619
ackA
Acetate kinase, putative; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.590
acoL
Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding.
 
 
0.569
SSA_1125
NADPH-dependent FMN reductase, putative; GC: 40.92%; Codon Adaptation Index (CAI): 0.795. Curator(s): J. Alves.
     
 0.554
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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